FZD10-AS1

Across TCGA pan-cancer cohorts, FZD10-AS1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of FZD10-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where FZD10-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types FZD10-AS1 is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.

THCA, KIRC, and BRCA are the cancer types where FZD10-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FZD10-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Female	III,IV	−0.721	<.001	11	view →
KIRC	Male	II,III,IV	−0.239	<.001	9	view →
BRCA	Female	II,III,IV	−0.801	<.001	6	view →
LIHC	All	All	+0.109	.002	3	view →
UCEC	All	All	+0.589	.038	2	view →
LUSC	All	All	+0.446	.016	2	view →
KIRP	All	All	−0.195	<.001	2	view →
KICH	All	III,IV	−0.401	.045	1	view →
STAD	Male	IV	−0.229	.046	1	view →
CHOL	Female	All	+0.216	.011	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

FZD10-AS1–THCA

Open the THCA breakdown →