FYCO1

Across TCGA pan-cancer cohorts, FYCO1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated FYCO1 data layer compared with 26 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher FYCO1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated FYCO1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and HNSC show a favorable association.

PDAC, GBM, and UCEC are the cancer types where FYCO1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	All	0.498	0.314	.001	53	view →
GBM	DFS	Tertile	All	0.594	0.858	<.001	33	view →
UCEC	OS	Tertile	III,IV	0.326	1.000	.013	16	view →
HNSC	OS	Median	All	1.000	0.449	.023	7	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

FYCO1–PDAC (DFS)

Open the PDAC breakdown →