FYCO1

Across TCGA patient cohorts, FYCO1 mutation is significantly associated with the RNA expression of many other genes, with 6,336 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FYCO1-associated genes across cancer lineages are RN7SL813P, HSPD1P2, and POLDIP3. Each is linked with FYCO1 in more than 3 cancer types. Because this analysis shows association rather than direction, both FYCO1-to-partner and partner-to-FYCO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL813P grouped by FYCO1-low versus FYCO1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FYCO1→partner) and Y-score (partner→FYCO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SL813P →	+0.101	+3.366	.001	.006	3	3
CESC	HSPD1P2 →	+0.041	+3.784	.007	.002	3	3
UCEC	POLDIP3 →	+0.495	+1.694	<.001	<.001	3	3
UCEC	BAG1 →	+0.492	+1.938	<.001	<.001	3	3
UCEC	BCCIP →	+0.286	+2.315	.001	<.001	3	3
UCEC	FTSJ3 →	+0.318	+1.874	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,336 associations by consensus.

RN7SL813P by FYCO1 expression — CESC

Explore this box plot interactively →