FYB1

Across TCGA patient cohorts, FYB1 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,313 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FYB1-associated proteins across cancer lineages are ARHGEF6_S225, PSMB10, and PTPN6. Each is linked with FYB1 in more than 9 cancer types. Because this analysis shows association rather than direction, both FYB1-to-partner and partner-to-FYB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FYB1 versus ARHGEF6_S225 in LSCC, with a Pearson correlation of 0.72.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FYB1→partner) and Y-score (partner→FYB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ARHGEF6_S225 →	+0.781	+1.085	<.001	<.001	3	10
LSCC	PSMB10 →	+0.542	+1.122	<.001	<.001	3	10
GBM	PTPN6 →	+0.715	+1.171	<.001	<.001	3	10
OV	PTPN7 →	+0.774	+1.421	<.001	<.001	3	10
GBM	PTPRC →	+0.881	+1.391	<.001	<.001	3	10
GBM	PTPRC_S975 →	+0.670	+1.145	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,313 associations by consensus.

FYB1 vs ARHGEF6_S225 — LSCC

Explore this scatter interactively →