Across TCGA pan-cancer cohorts, FXYD7 mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated FXYD7 data layer compared with 20 for mass-spec protein and 2 for mutation status.
The strongest signal is observed in glioblastoma multiforme (GBM), where higher FXYD7 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated FXYD7 expression acts as an unfavorable survival marker, although some lineages such as GBM show a favorable association.
GBM are the cancer types where FXYD7 mass-spec protein most reproducibly stratifies survival.