Across TCGA patient cohorts, FXYD7 mutation is significantly associated with the RNA expression of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FXYD7-associated genes across cancer lineages are VN1R18P, E2F6P1, and RNU7-54P. Each is linked with FXYD7 in more than 1 cancer types. Because this analysis shows association rather than direction, both FXYD7-to-partner and partner-to-FXYD7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FXYD7→partner) and Y-score (partner→FXYD7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	VN1R18P →	+0.045	+6.993	<.001	<.001	3	1
SKCM	E2F6P1 →	+0.052	+5.594	<.001	.004	3	1
SKCM	RNU7-54P →	+0.498	+5.771	<.001	.003	3	1
SKCM	RN7SL675P →	+0.132	+6.080	<.001	.002	3	1
SKCM	RN7SL541P →	+0.192	+5.159	<.001	.007	3	1
SKCM	UBA52P9 →	+0.107	+5.513	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

Exploration

FXYD7 survival (RNA) · tumor vs normal (RNA) · all FXYD7 data types