FXYD6P3

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, FXYD6P3 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated FXYD6P3 data layer compared with 9 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher FXYD6P3 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FXYD6P3 expression acts as an unfavorable survival marker.

COAD and LUAD are the cancer types where FXYD6P3 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
COADOSMedianAll0.2340.809.00224view →
LUADOSMedianAll0.0790.788<.00120view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

FXYD6P3–COAD (OS)

Kaplan–Meier survival curve for FXYD6P3 mutant vs wild-type samples in COAD.

Open the COAD breakdown →

Exploration