FXYD6P2

Across TCGA pan-cancer cohorts, FXYD6P2 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated FXYD6P2 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher FXYD6P2 RNA is associated with better overall survival. In most high-consensus cancer types, elevated FXYD6P2 expression acts as an unfavorable survival marker, although some lineages such as HNSC and PAAD show a favorable association.

HNSC, CHOL, and KIRC are the cancer types where FXYD6P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	All	0.891	0.737	.008	45	view →
CHOL	OS	Tertile	All	0.019	0.800	<.001	36	view →
KIRC	OS	Tertile	All	0.529	0.665	.006	26	view →
PCPG	OS	Tertile	All	0.899	0.992	.003	24	view →
UCEC	DFS	Tertile	All	0.332	0.686	.020	24	view →
THCA	DFS	Tertile	All	0.867	0.948	.010	18	view →
COAD	DFS	Tertile	II,III,IV	0.186	0.474	.019	15	view →
STAD	DFS	Tertile	IV	0.160	0.402	.044	9	view →
DLBC	OS	Tertile	III,IV	0.272	1.000	.038	9	view →
KICH	OS	Tertile	II,III,IV	0.468	0.927	.026	9	view →
LUSC	DFS	Tertile	III,IV	0.143	0.607	.029	9	view →
PAAD	OS	Tertile	All	0.682	0.351	.026	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

FXYD6P2–HNSC (OS)

Open the HNSC breakdown →