FXYD6

Across TCGA patient cohorts, FXYD6 protein abundance is significantly associated with the RNA expression of many other genes, with 3,976 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FXYD6-associated genes across cancer lineages are SERINC2, MICU1, and PACSIN1. Each is linked with FXYD6 in more than 1 cancer types. Because this analysis shows association rather than direction, both FXYD6-to-partner and partner-to-FXYD6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FXYD6 versus SERINC2 in UCEC, with a Pearson correlation of -0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FXYD6→partner) and Y-score (partner→FXYD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SERINC2 →	-1.862	-0.880	<.001	.001	3	2
OV	MICU1 →	+0.506	+1.074	.001	.001	3	2
GBM	PACSIN1 →	+1.331	+0.516	<.001	<.001	3	2
OV	LRRC38 →	+0.431	+1.291	.002	<.001	3	2
GBM	MARCKSL1 →	+0.760	+0.449	.003	.006	3	2
GBM	MAP6D1 →	+0.459	+0.395	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,976 associations by consensus.

FXYD6 vs SERINC2 — UCEC

Explore this scatter interactively →