FXYD5

Across TCGA cell cohorts, FXYD5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,200 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible FXYD5-associated GO terms across cancer lineages are Actin filament organization, Microvillus assembly, and Regulation of proteolysis. Each is linked with FXYD5 in more than 14 cancer types. Because this analysis shows association rather than direction, both FXYD5-to-partner and partner-to-FXYD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Actin filament organization grouped by FXYD5-low versus FXYD5-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FXYD5→partner) and Y-score (partner→FXYD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Actin filament organization →	+0.118	+3.164	<.001	<.001	3	15
LIVER	Microvillus assembly →	+0.331	+4.662	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Regulation of proteolysis →	+0.117	+3.361	<.001	.002	3	15
LUNG_NSCLC_LUSC	Regulation of coagulation →	+0.255	+4.202	<.001	.001	3	15
BONE	Cell-substrate adhesion →	+0.179	+4.646	<.001	<.001	3	15
BONE	Integrin-mediated signaling pathway →	+0.224	+3.529	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,200 associations by consensus.

Actin filament organization by FXYD5 expression — BONE

Explore this box plot interactively →