FXYD3

Across TCGA patient cohorts, FXYD3 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,698 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FXYD3-associated proteins across cancer lineages are EPB41L1, PDZRN3_S848, and MYH14. Each is linked with FXYD3 in more than 5 cancer types. Because this analysis shows association rather than direction, both FXYD3-to-partner and partner-to-FXYD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FXYD3 versus EPB41L1 in LSCC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FXYD3→partner) and Y-score (partner→FXYD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	EPB41L1 →	+0.635	+0.955	<.001	.004	3	6
OV	PDZRN3_S848 →	-0.955	-0.444	<.001	<.001	3	5
HNSC	MYH14 →	+0.573	+0.636	<.001	<.001	3	5
OV	CDH1 →	+0.471	+0.336	.001	.008	3	5
HNSC	CORO2A →	+0.523	+1.034	<.001	<.001	3	5
LSCC	CTNND1 →	+0.244	+1.188	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,698 associations by consensus.

FXYD3 vs EPB41L1 — LSCC

Explore this scatter interactively →