FXYD3

Across TCGA patient cohorts, FXYD3 protein abundance is significantly associated with the RNA expression of many other genes, with 1,060 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FXYD3-associated genes across cancer lineages are SNORA77, RN7SKP263, and GPR42. Each is linked with FXYD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both FXYD3-to-partner and partner-to-FXYD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FXYD3 versus SNORA77 in UCEC, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FXYD3→partner) and Y-score (partner→FXYD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNORA77 →	+1.518	+0.734	<.001	.009	3	2
GBM	RN7SKP263 →	-0.761	-0.723	.004	.001	3	2
COAD	GPR42 →	+0.172	+0.415	.007	.003	3	2
UCEC	UPB1 →	+0.178	+1.115	.002	.001	3	1
UCEC	EIF3L →	-1.021	-0.929	<.001	<.001	3	1
UCEC	POLR2F →	-0.675	-0.734	.006	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,060 associations by consensus.

FXYD3 vs SNORA77 — UCEC

Explore this scatter interactively →