FXYD3

Across TCGA patient cohorts, FXYD3 protein abundance is significantly associated with the protein abundance of many other proteins, with 1,502 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FXYD3-associated proteins across cancer lineages are PLEC_S1043, NCF1, and NCF4. Each is linked with FXYD3 in more than 2 cancer types. Because this analysis shows association rather than direction, both FXYD3-to-partner and partner-to-FXYD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FXYD3 versus PLEC_S1043 in UCEC, with a Pearson correlation of 1.00.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FXYD3→partner) and Y-score (partner→FXYD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PLEC_S1043 →	+1.027	+1.027	<.001	<.001	3	3
GBM	NCF1 →	+0.823	+0.805	.001	<.001	3	2
GBM	NCF4 →	+0.696	+0.718	.002	.001	3	2
GBM	BICC1_S633 →	+0.782	+0.723	.003	.001	3	1
GBM	BIN2 →	+1.025	+0.994	.002	.001	3	1
GBM	BIN2_S425 →	+1.164	+0.779	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,502 associations by consensus.

FXYD3 vs PLEC_S1043 — UCEC

Explore this scatter interactively →