FXYD3

Across TCGA patient cohorts, FXYD3 mutation is significantly associated with the RNA expression of many other genes, with 2,384 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FXYD3-associated genes across cancer lineages are RN7SL237P, DDX43P3, and MTND3P13. Each is linked with FXYD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both FXYD3-to-partner and partner-to-FXYD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL237P grouped by FXYD3-low versus FXYD3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FXYD3→partner) and Y-score (partner→FXYD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL237P →	+0.247	+2.036	<.001	.003	3	2
COAD	DDX43P3 →	+0.085	+4.537	.008	.006	3	2
COAD	MTND3P13 →	+0.128	+4.308	<.001	.009	3	2
BRCA	RNA5SP528 →	+0.364	+5.332	<.001	.001	3	1
BRCA	MIR6737 →	+0.489	+4.506	<.001	.009	3	1
BRCA	RNU6-751P →	+0.146	+7.473	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,384 associations by consensus.

RN7SL237P by FXYD3 expression — UCEC

Explore this box plot interactively →