FXYD3

Across TCGA cell cohorts, FXYD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,744 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible FXYD3-associated GO terms across cancer lineages are Positive regulation of iron ion transport, Positive regulation of iron ion transmembrane transport, and Positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay. Each is linked with FXYD3 in more than 11 cancer types. Because this analysis shows association rather than direction, both FXYD3-to-partner and partner-to-FXYD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of iron ion transport grouped by FXYD3-low versus FXYD3-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FXYD3→partner) and Y-score (partner→FXYD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Positive regulation of iron ion transport →	+1.577	+5.862	.002	<.001	3	12
LUNG_NSCLC_LUSC	Positive regulation of iron ion transmembrane transport →	+1.577	+5.862	.002	<.001	3	12
URINARY_TRACT	Positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.167	+5.205	<.001	<.001	3	11
LUNG_SCLC	Positive regulation of potassium ion import across plasma membrane →	+0.245	+2.389	<.001	.008	3	11
LUNG_NSCLC_LUSC	Regulation of inner ear receptor cell differentiation →	+1.534	+6.919	.001	<.001	3	11
LUNG_NSCLC_LUSC	Cytotoxic T cell degranulation →	+0.321	+5.831	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,744 associations by consensus.

Positive regulation of iron ion transport by FXYD3 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →