FXYD2

Across TCGA patient cohorts, FXYD2 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,359 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FXYD2-associated proteins across cancer lineages are AGO1, DDAH1, and FERMT2. Each is linked with FXYD2 in more than 4 cancer types. Because this analysis shows association rather than direction, both FXYD2-to-partner and partner-to-FXYD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FXYD2 versus AGO1 in UCEC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FXYD2→partner) and Y-score (partner→FXYD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	AGO1 →	+0.308	+0.572	.001	.003	3	5
HNSC	DDAH1 →	+0.482	+0.344	<.001	.001	3	5
UCEC	FERMT2 →	+0.801	+0.713	<.001	<.001	3	5
COAD	QKI →	+0.235	+0.066	.002	.001	2	5
HNSC	MYEF2 →	+0.803	+0.331	<.001	.009	2	5
GBM	S100A11 →	-0.887	-0.903	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,359 associations by consensus.

FXYD2 vs AGO1 — UCEC

Explore this scatter interactively →