FXYD2

Across TCGA cell cohorts, FXYD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,018 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FXYD2-associated GO terms across cancer lineages are Positive regulation of collagen metabolic process, Response to carbon monoxide, and Regulation of kidney size. Each is linked with FXYD2 in more than 5 cancer types. Because this analysis shows association rather than direction, both FXYD2-to-partner and partner-to-FXYD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of collagen metabolic process grouped by FXYD2-low versus FXYD2-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FXYD2→partner) and Y-score (partner→FXYD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Positive regulation of collagen metabolic process →	-0.157	-3.764	.002	.003	3	6
UPPER_AERODIGESTIVE_TRACT	Response to carbon monoxide →	-0.203	-0.626	<.001	.006	3	5
OVARY	Regulation of kidney size →	+1.379	+3.162	<.001	<.001	3	5
BLOOD_Leukemia	Regulation of isotype switching to IgE isotypes →	+0.773	+2.117	<.001	.001	3	5
BLOOD_Leukemia	Positive regulation of isotype switching to IgE isotypes →	+0.773	+2.117	<.001	.001	3	5
BLOOD_Leukemia	Galactolipid catabolic process →	-0.622	-1.825	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,018 associations by consensus.

Positive regulation of collagen metabolic process by FXYD2 expression — KIDNEY

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