FXYD1

Across TCGA pan-cancer cohorts, FXYD1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated FXYD1 data layer compared with 24 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher FXYD1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated FXYD1 expression acts as an unfavorable survival marker.

CCRCC, UCEC, and HNSC are the cancer types where FXYD1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Quartile	II,III,IV	0.257	0.733	.003	24	view →
UCEC	DFS	Quartile	All	0.787	1.000	.013	8	view →
HNSC	OS	Median	II,III,IV	0.932	1.000	.016	7	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

FXYD1–CCRCC (DFS)

Open the CCRCC breakdown →