FXR2

Across TCGA patient cohorts, FXR2 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,134 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FXR2-associated proteins across cancer lineages are YWHAE, RPAIN, and SPAG7. Each is linked with FXR2 in more than 6 cancer types. Because this analysis shows association rather than direction, both FXR2-to-partner and partner-to-FXR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FXR2 versus YWHAE in OV, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FXR2→partner) and Y-score (partner→FXR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	YWHAE →	+0.289	+0.420	<.001	<.001	3	7
LSCC	RPAIN →	+0.449	+0.544	<.001	<.001	3	6
COAD	SPAG7 →	+0.324	+0.364	<.001	.004	3	6
GBM	NCOR1 →	+0.239	+0.371	.003	<.001	3	5
BRCA	UBE2G1 →	+0.257	+0.480	<.001	<.001	3	5
LUAD	SMG6 →	+0.222	+0.429	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,134 associations by consensus.

FXR2 vs YWHAE — OV

Explore this scatter interactively →