FXR2

Across TCGA patient cohorts, FXR2 protein abundance is significantly associated with the RNA expression of many other genes, with 11,328 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FXR2-associated genes across cancer lineages are RANGRF, UBE2G1, and CENPV. Each is linked with FXR2 in more than 8 cancer types. Because this analysis shows association rather than direction, both FXR2-to-partner and partner-to-FXR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FXR2 versus RANGRF in BRCA, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FXR2→partner) and Y-score (partner→FXR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RANGRF →	+0.395	+0.249	<.001	<.001	3	8
HNSC	UBE2G1 →	+0.688	+0.275	<.001	<.001	2	9
GBM	CENPV →	+1.062	+0.218	<.001	.001	3	7
LSCC	TOP3A →	+0.619	+0.245	<.001	<.001	3	7
HNSC	DHX33 →	+0.827	+0.326	<.001	<.001	3	7
HNSC	PAFAH1B1 →	+0.589	+0.215	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,328 associations by consensus.

FXR2 vs RANGRF — BRCA

Explore this scatter interactively →