FXR2

Across TCGA patient cohorts, FXR2 mutation is significantly associated with the RNA expression of many other genes, with 1,098 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FXR2-associated genes across cancer lineages are RNU1-62P, PRELID3BP1, and HMGB3P3. Each is linked with FXR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FXR2-to-partner and partner-to-FXR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-62P grouped by FXR2-low versus FXR2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FXR2→partner) and Y-score (partner→FXR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU1-62P →	+0.164	+4.282	<.001	.009	3	2
SKCM	PRELID3BP1 →	+0.208	+4.402	<.001	.002	3	2
UCEC	HMGB3P3 →	+0.151	+2.021	<.001	.001	3	2
BRCA	RNA5SP463 →	+0.300	+3.928	<.001	.002	3	2
BRCA	COMMD4P2 →	+0.069	+3.726	.004	.005	3	2
BRCA	MIR8061 →	+0.224	+4.215	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,098 associations by consensus.

RNU1-62P by FXR2 expression — SKCM

Explore this box plot interactively →