FXR2

Across TCGA cell cohorts, FXR2 mutation is significantly associated with the RNA expression of many other genes, with 516 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FXR2-associated genes across cancer lineages are SLC30A2, CCDC190, and KRTAP2-1. Each is linked with FXR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FXR2-to-partner and partner-to-FXR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC30A2 grouped by FXR2-low versus FXR2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FXR2→partner) and Y-score (partner→FXR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	SLC30A2 →	+0.029	+3.843	<.001	.007	3	1
BLOOD_Lymphoma	CCDC190 →	+0.063	+3.843	.001	.007	3	1
BLOOD_Lymphoma	KRTAP2-1 →	+0.051	+4.058	<.001	.009	3	1
BLOOD_Lymphoma	PSG11 →	+0.058	+3.714	<.001	.006	3	1
BLOOD_Leukemia	GML →	+0.099	+4.152	<.001	.009	3	1
BLOOD_Leukemia	MMP27 →	+0.019	+4.969	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 516 associations by consensus.

SLC30A2 by FXR2 expression — BLOOD_Lymphoma

Explore this box plot interactively →