FXR1

Across TCGA patient cohorts, FXR1 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,307 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FXR1-associated proteins across cancer lineages are UBXN7, POLR2H, and TBL1XR1. Each is linked with FXR1 in more than 6 cancer types. Because this analysis shows association rather than direction, both FXR1-to-partner and partner-to-FXR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FXR1 versus UBXN7 in LSCC, with a Pearson correlation of 0.70.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FXR1→partner) and Y-score (partner→FXR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	UBXN7 →	+0.579	+0.951	<.001	<.001	3	7
LSCC	POLR2H →	+0.381	+0.783	<.001	<.001	3	7
LSCC	TBL1XR1 →	+0.482	+0.846	<.001	<.001	3	7
UCEC	ZNF148 →	+0.239	+0.431	<.001	<.001	3	6
LSCC	U2SURP →	+0.242	+0.697	<.001	<.001	3	6
LSCC	PAK2 →	+0.250	+0.621	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,307 associations by consensus.

FXR1 vs UBXN7 — LSCC

Explore this scatter interactively →