FXR1

Across TCGA cell cohorts, FXR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,524 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FXR1-associated GO terms across cancer lineages are Protein localization to chromosome, Response to arsenite ion, and Cellular response to arsenite ion. Each is linked with FXR1 in more than 14 cancer types. Because this analysis shows association rather than direction, both FXR1-to-partner and partner-to-FXR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to chromosome grouped by FXR1-low versus FXR1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FXR1→partner) and Y-score (partner→FXR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Protein localization to chromosome →	+0.088	+0.538	.003	.007	2	15
OVARY	Response to arsenite ion →	+0.119	+0.841	<.001	.001	3	14
OVARY	Cellular response to arsenite ion →	+0.119	+0.841	<.001	.001	3	14
SKIN	Somatic recombination of immunoglobulin gene segments →	+0.077	+0.524	<.001	.001	3	13
LUNG_NSCLC_LUSC	Protein localization to nucleus →	+0.047	+1.482	<.001	.001	3	12
SOFT_TISSUE	Spindle organization →	+0.066	+0.516	<.001	.002	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,524 associations by consensus.

Protein localization to chromosome by FXR1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →