FXNP2

Across TCGA pan-cancer cohorts, FXNP2 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of FXNP2’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where FXNP2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FXNP2 is over-expressed in tumor, although a few such as KICH and KIRP show the opposite, repressed pattern.

COAD, HNSC, and BRCA are the cancer types where FXNP2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FXNP2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+0.116	<.001	5	view →
HNSC	All	IV	+0.058	.035	3	view →
BRCA	All	All	+0.076	.023	2	view →
STAD	All	II,III,IV	+0.129	.024	1	view →
KICH	Male	All	−0.081	.033	1	view →
KIRP	Male	All	−0.054	.041	1	view →
LIHC	Female	All	−0.032	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

FXNP2–COAD

Open the COAD breakdown →