FUT9

Across TCGA pan-cancer cohorts, FUT9 Mutation is linked to patient survival in 10 of 34 cancer types, making it a survival-associated FUT9 data layer compared with 16 for mass-spec protein.

The strongest signal is observed in thymoma (THYM), where higher FUT9 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FUT9 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

THYM, READ, and KIRC are the cancer types where FUT9 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Median	III,IV	0.103	0.944	<.001	42	view →
READ	OS	Median	II,III,IV	0.111	0.919	<.001	30	view →
KIRC	OS	Median	All	0.172	0.805	.001	24	view →
LUAD	OS	Median	All	0.299	0.675	.009	15	view →
UCEC	DFS	Median	II,III,IV	0.904	0.432	.018	10	view →
ESCA	DFS	Median	II,III,IV	0.305	0.544	.010	9	view →
TGCT	DFS	Median	All	0.066	0.802	<.001	6	view →
LUSC	DFS	Median	All	0.510	0.755	.008	6	view →
COAD	OS	Median	III,IV	0.173	0.548	.043	2	view →
SARC	DFS	Median	All	0.176	0.399	.047	1	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

FUT9–THYM (OS)

Open the THYM breakdown →