FUT6

Across TCGA cell cohorts, FUT6 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,205 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FUT6-associated GO terms across cancer lineages are Positive regulation of endoplasmic reticulum unfolded protein response, Establishment or maintenance of microtubule cytoskeleton polarity, and Cytotoxic T cell degranulation. Each is linked with FUT6 in more than 8 cancer types. Because this analysis shows association rather than direction, both FUT6-to-partner and partner-to-FUT6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of endoplasmic reticulum unfolded protein response grouped by FUT6-low versus FUT6-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FUT6→partner) and Y-score (partner→FUT6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of endoplasmic reticulum unfolded protein response →	+0.079	+0.716	.002	.001	3	9
PANCREAS	Establishment or maintenance of microtubule cytoskeleton polarity →	-0.144	-0.819	<.001	.003	3	7
OVARY	Cytotoxic T cell degranulation →	+0.224	+0.149	<.001	.009	2	8
STOMACH	Cellular response to ketone →	+0.097	+1.636	<.001	.009	3	7
URINARY_TRACT	Multivesicular body assembly →	+0.081	+0.377	.001	.009	3	7
PANCREAS	Viral budding →	+0.081	+0.794	<.001	.005	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,205 associations by consensus.

Positive regulation of endoplasmic reticulum unfolded protein response by FUT6 expression — OESOPHAGUS

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