FUT5

Across TCGA pan-cancer cohorts, FUT5 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated FUT5 data layer compared with 17 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher FUT5 Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated FUT5 expression acts as an unfavorable survival marker, although some lineages such as LUSC and SKCM show a favorable association.

LUSC, SKCM, and LIHC are the cancer types where FUT5 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Median	All	0.844	0.380	.006	16	view →
SKCM	OS	Median	III,IV	0.736	0.375	.017	13	view →
LIHC	OS	Median	All	0.507	0.777	<.001	10	view →
LUAD	OS	Median	II,III,IV	0.090	0.677	<.001	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

FUT5–LUSC (DFS)

Open the LUSC breakdown →