FUT5

Across TCGA patient cohorts, FUT5 mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible FUT5-associated genes across cancer lineages are GSK3-a-b, Chk2, and GATA3. Each is linked with FUT5 in more than 1 cancer types. Because this analysis shows association rather than direction, both FUT5-to-partner and partner-to-FUT5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GSK3-a-b grouped by FUT5-low versus FUT5-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FUT5→partner) and Y-score (partner→FUT5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	GSK3-a-b →	+0.181	+3.027	.036	.018	3	1
LUSC	Chk2 →	+0.372	+3.179	.005	.010	3	1
SKCM	GATA3 →	-0.179	-2.115	.031	.018	3	1
SKCM	MYH11 →	-0.769	-3.169	.040	.018	3	1
SKCM	DJ-1 →	+0.166	+3.169	.034	.018	3	1
UCEC	JNK2 →	+0.291	+3.009	.001	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

GSK3-a-b by FUT5 expression — LUSC

Explore this box plot interactively →