Across TCGA pan-cancer cohorts, FUT4 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated FUT4 data layer compared with 23 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher FUT4 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated FUT4 expression acts as an unfavorable survival marker, although some lineages such as PDAC show a favorable association.

LSCC and PDAC are the cancer types where FUT4 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Tertile	All	0.339	1.000	.001	25	view →
PDAC	OS	Quartile	II,III,IV	0.705	0.389	.018	11	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: FUT4 tumor-vs-normal RNA expression · all FUT4 data types