Across TCGA cell cohorts, FUT4 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FUT4-associated genes across cancer lineages are OR51E1, VCY1B, and RBMY1A1. Each is linked with FUT4 in more than 1 cancer types. Because this analysis shows association rather than direction, both FUT4-to-partner and partner-to-FUT4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FUT4→partner) and Y-score (partner→FUT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	OR51E1 →	+0.014	+3.906	<.001	.009	3	1
OVARY	VCY1B →	+0.288	+4.029	<.001	.009	3	1
OVARY	RBMY1A1 →	+0.107	+4.807	<.001	.003	3	1
LUNG_SCLC	OR9I1 →	+0.017	+4.643	<.001	.004	3	1
LUNG_SCLC	PRB1 →	+0.038	+4.523	<.001	.003	3	1
LARGE_INTESTINE	UCP1 →	+0.239	+3.660	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

FUT4 survival (RNA) · tumor vs normal (RNA) · all FUT4 data types