FUT3

Across TCGA pan-cancer cohorts, FUT3 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated FUT3 data layer compared with 20 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in sarcoma (SARC), where higher FUT3 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FUT3 expression acts as an unfavorable survival marker, although some lineages such as UCEC and SKCM show a favorable association.

SARC, UCEC, and STAD are the cancer types where FUT3 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SARC	OS	Median	All	0.085	0.839	<.001	12	view →
UCEC	DFS	Median	All	0.963	0.616	.008	10	view →
STAD	OS	Median	III,IV	0.213	0.635	.010	8	view →
LUAD	OS	Median	All	0.313	0.700	.008	6	view →
SKCM	OS	Median	II,III,IV	1.000	0.834	.042	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

FUT3–SARC (OS)

Open the SARC breakdown →