FUT2

Across TCGA cell cohorts, FUT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,108 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FUT2-associated GO terms across cancer lineages are Regulation of cardiac muscle cell action potential, Regulation of potassium ion import, and Desmosome assembly. Each is linked with FUT2 in more than 10 cancer types. Because this analysis shows association rather than direction, both FUT2-to-partner and partner-to-FUT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cardiac muscle cell action potential grouped by FUT2-low versus FUT2-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FUT2→partner) and Y-score (partner→FUT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of cardiac muscle cell action potential →	+0.146	+2.672	<.001	<.001	3	11
STOMACH	Regulation of potassium ion import →	+0.314	+3.602	<.001	<.001	3	10
LUNG_SCLC	Desmosome assembly →	+0.387	+1.246	.002	<.001	3	10
STOMACH	Cell-cell adhesion mediated by cadherin →	+0.213	+3.307	.004	<.001	3	10
STOMACH	Regulation of cardiac muscle contraction →	+0.157	+3.695	<.001	<.001	3	10
STOMACH	Regulation of striated muscle contraction →	+0.130	+2.517	.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,108 associations by consensus.

Regulation of cardiac muscle cell action potential by FUT2 expression — STOMACH

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