FUT10

Across TCGA pan-cancer cohorts, FUT10 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated FUT10 data layer compared with 22 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher FUT10 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FUT10 expression acts as an unfavorable survival marker.

SKCM, KIRC, and HNSC are the cancer types where FUT10 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Median	III,IV	0.072	0.814	<.001	13	view →
KIRC	OS	Median	All	0.152	0.874	<.001	12	view →
HNSC	OS	Median	All	0.167	0.710	.005	12	view →
LGG	OS	Median	All	0.182	0.909	<.001	6	view →
BLCA	DFS	Median	IV	0.142	0.471	.014	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

FUT10–SKCM (OS)

Open the SKCM breakdown →