FUOM

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, FUOM mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated FUOM data layer compared with 20 for mass-spec protein.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher FUOM mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated FUOM expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LUAD show a favorable association.

CCRCC, PDAC, and LUAD are the cancer types where FUOM mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CCRCCOSMedianIV1.0000.451.01611view →
PDACDFSTertileII,III,IV0.4290.670.0276view →
LUADDFSTertileII,III,IV0.6570.344.0366view →
LSCCOSQuartileII,III,IV0.6420.996.0183view →
HNSCDFSMedianIV1.0000.910.0412view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

FUOM–CCRCC (OS)

Kaplan–Meier survival curve for FUOM mass-spec protein-high vs -low samples in CCRCC.

Open the CCRCC breakdown →

Exploration