FUOM

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FUOM RNA expression is significantly associated with the protein abundance of many other proteins, with 10,798 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FUOM-associated proteins across cancer lineages are WAS, BLNK_S129, and C1QA. Each is linked with FUOM in more than 3 cancer types. Because this analysis shows association rather than direction, both FUOM-to-partner and partner-to-FUOM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FUOM versus WAS in GBM, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FUOM→partner) and Y-score (partner→FUOM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMWAS →+0.563+0.601<.001<.00134
LUADBLNK_S129 →+0.606+0.630<.001.00134
GBMC1QA →+0.620+0.762.002<.00134
GBMS100A4 →+0.882+0.756<.001<.00134
COADMSI2 →-0.464-0.990<.001<.00134
GBMCAPZA1 →+0.334+0.869<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,798 associations by consensus.

FUOM vs WAS — GBM

Per-sample scatter of FUOM vs WAS in GBM (Pearson r = 0.56).

Explore this scatter interactively →

Exploration