FUOM

Across TCGA patient cohorts, FUOM protein abundance is significantly associated with the RNA expression of many other genes, with 3,567 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible FUOM-associated genes across cancer lineages are LCP2, RSKR, and SEC23B. Each is linked with FUOM in more than 2 cancer types. Because this analysis shows association rather than direction, both FUOM-to-partner and partner-to-FUOM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FUOM versus LCP2 in LUAD, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FUOM→partner) and Y-score (partner→FUOM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	LCP2 →	+0.638	+0.442	.008	.003	3	3
BRCA	RSKR →	-0.418	-0.379	.001	<.001	3	3
LUAD	SEC23B →	-0.524	-0.441	<.001	<.001	3	2
LSCC	IDH3B →	-0.326	-0.269	.002	.006	3	2
LUAD	TGFB1 →	+0.708	+0.500	<.001	.002	3	2
LUAD	CD33 →	+0.607	+0.544	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,567 associations by consensus.

FUOM vs LCP2 — LUAD

Explore this scatter interactively →