FUOM

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FUOM RNA expression is significantly associated with the go_rna of many other GO terms, with 2,918 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FUOM-associated GO terms across cancer lineages are GDP-L-fucose biosynthetic process, GDP-L-fucose metabolic process, and Mitochondrial ribosome assembly. Each is linked with FUOM in more than 8 cancer types. Because this analysis shows association rather than direction, both FUOM-to-partner and partner-to-FUOM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GDP-L-fucose biosynthetic process grouped by FUOM-low versus FUOM-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FUOM→partner) and Y-score (partner→FUOM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCGDP-L-fucose biosynthetic process →+0.103+1.510<.001.00239
LUNG_SCLCGDP-L-fucose metabolic process →+0.091+1.601.001.00137
URINARY_TRACTMitochondrial ribosome assembly →+0.106+1.983<.001.00536
OESOPHAGUSProtein-lipid complex organization →+0.110+2.227.001<.00136
OESOPHAGUSPlasma lipoprotein particle organization →+0.102+2.262.005<.00136
BONEResponse to corticotropin-releasing hormone →+1.187+1.364.002.00527
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,918 associations by consensus.

GDP-L-fucose biosynthetic process by FUOM expression — LUNG_SCLC

Box plot of GDP-L-fucose biosynthetic process in FUOM-low vs FUOM-high samples in LUNG_SCLC.

Explore this box plot interactively →

Exploration