FUNDC2

Across TCGA patient cohorts, FUNDC2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,162 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FUNDC2-associated proteins across cancer lineages are PHF6, CETN2, and EMD. Each is linked with FUNDC2 in more than 4 cancer types. Because this analysis shows association rather than direction, both FUNDC2-to-partner and partner-to-FUNDC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FUNDC2 versus PHF6 in GBM, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FUNDC2→partner) and Y-score (partner→FUNDC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PHF6 →	+0.493	+0.298	<.001	.001	3	5
BRCA	CETN2 →	+0.400	+0.468	<.001	<.001	3	5
BRCA	EMD →	+0.393	+0.394	<.001	.001	3	5
GBM	TCEAL4 →	+0.514	+0.380	<.001	<.001	3	4
GBM	TSR2 →	+0.371	+0.299	<.001	<.001	3	4
GBM	PLCG2 →	-0.460	-0.223	.004	.009	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,162 associations by consensus.

FUNDC2 vs PHF6 — GBM

Explore this scatter interactively →