FUNDC1

Across TCGA patient cohorts, FUNDC1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,288 significant associations in total. COAD shows the largest number of these associations.

The most reproducible FUNDC1-associated genes across cancer lineages are AURKB, RASSF1, and MAP7D1. Each is linked with FUNDC1 in more than 4 cancer types. Because this analysis shows association rather than direction, both FUNDC1-to-partner and partner-to-FUNDC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FUNDC1 versus AURKB in BRCA, with a Pearson correlation of -0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FUNDC1→partner) and Y-score (partner→FUNDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	AURKB →	-1.674	-0.762	<.001	<.001	3	5
UCEC	RASSF1 →	-0.655	-0.275	.001	.001	3	5
BRCA	MAP7D1 →	-0.867	-0.570	<.001	.003	3	4
UCEC	STAG1 →	-0.535	-0.465	<.001	<.001	3	4
UCEC	PIMREG →	-1.099	-0.467	.001	<.001	3	4
BRCA	KIF2C →	-1.287	-0.703	.005	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,288 associations by consensus.

FUNDC1 vs AURKB — BRCA

Explore this scatter interactively →