FUNDC1

Across TCGA cell cohorts, FUNDC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,425 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible FUNDC1-associated GO terms across cancer lineages are Growth hormone secretion, ATP synthesis coupled electron transport, and Mitochondrial ATP synthesis coupled electron transport. Each is linked with FUNDC1 in more than 11 cancer types. Because this analysis shows association rather than direction, both FUNDC1-to-partner and partner-to-FUNDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Growth hormone secretion grouped by FUNDC1-low versus FUNDC1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FUNDC1→partner) and Y-score (partner→FUNDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Growth hormone secretion →	+0.133	+0.815	.003	.002	3	12
UPPER_AERODIGESTIVE_TRACT	ATP synthesis coupled electron transport →	+0.089	+0.640	<.001	.003	3	9
UPPER_AERODIGESTIVE_TRACT	Mitochondrial ATP synthesis coupled electron transport →	+0.089	+0.640	<.001	.003	3	9
BLOOD_Myeloma	Negative regulation of heterochromatin organization →	+0.128	+0.881	<.001	.001	3	9
BLOOD_Myeloma	Negative regulation of heterochromatin formation →	+0.128	+0.881	<.001	.001	3	9
BLOOD_Myeloma	Regulation of heterochromatin organization →	+0.092	+0.880	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,425 associations by consensus.

Growth hormone secretion by FUNDC1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →