FUCA1

Across TCGA pan-cancer cohorts, FUCA1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated FUCA1 data layer compared with 27 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher FUCA1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated FUCA1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and PDAC show a favorable association.

UCEC, PDAC, and HNSC are the cancer types where FUCA1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	All	1.000	0.901	.005	18	view →
PDAC	DFS	Quartile	All	0.553	0.273	.020	12	view →
HNSC	OS	Tertile	II,III,IV	0.923	1.000	.009	9	view →
CCRCC	OS	Quartile	All	1.000	0.878	.017	6	view →
LUAD	DFS	Quartile	All	0.772	0.996	.008	5	view →
OV	DFS	Median	All	0.647	0.907	.035	4	view →
LSCC	OS	Quartile	III,IV	1.000	0.583	.019	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

FUCA1–UCEC (OS)

Open the UCEC breakdown →