FUCA1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FUCA1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,066 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FUCA1-associated genes across cancer lineages are MLPH, TMEM59, and HROB. Each is linked with FUCA1 in more than 6 cancer types. Because this analysis shows association rather than direction, both FUCA1-to-partner and partner-to-FUCA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FUCA1 versus MLPH in BRCA, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FUCA1→partner) and Y-score (partner→FUCA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAMLPH →+2.384+0.588<.001<.00137
BRCATMEM59 →+0.501+0.560<.001<.00136
LSCCHROB →-0.929-0.415<.001<.00136
BRCADEPTOR →+1.220+0.740<.001<.00136
HNSCPRR15L →+1.316+0.741<.001<.00136
LUADFCER1A →+1.488+0.579<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,066 associations by consensus.

FUCA1 vs MLPH — BRCA

Per-sample scatter of FUCA1 vs MLPH in BRCA (Pearson r = 0.61).

Explore this scatter interactively →

Exploration