FUBP3

Across TCGA patient cohorts, FUBP3 mutation is significantly associated with the RNA expression of many other genes, with 5,832 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FUBP3-associated genes across cancer lineages are SNRPCP20, DRD2, and SLC7A11. Each is linked with FUBP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both FUBP3-to-partner and partner-to-FUBP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNRPCP20 grouped by FUBP3-low versus FUBP3-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FUBP3→partner) and Y-score (partner→FUBP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SNRPCP20 →	+0.190	+5.045	.002	.009	3	2
UCEC	DRD2 →	-0.432	-2.300	.001	<.001	3	2
UCEC	SLC7A11 →	+0.726	+3.818	.001	<.001	3	2
UCEC	NOCT →	+0.674	+2.010	<.001	<.001	3	2
UCEC	CENPU →	+0.953	+2.032	<.001	<.001	3	2
UCEC	SLC25A4 →	+0.599	+2.711	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,832 associations by consensus.

SNRPCP20 by FUBP3 expression — BRCA

Explore this box plot interactively →