FUBP3

Across TCGA patient cohorts, FUBP3 mutation is significantly associated with the total protein of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FUBP3-associated genes across cancer lineages are Gab2, INPP4B, and Notch1. Each is linked with FUBP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both FUBP3-to-partner and partner-to-FUBP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Gab2 grouped by FUBP3-low versus FUBP3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FUBP3→partner) and Y-score (partner→FUBP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Gab2 →	+0.332	+2.000	.008	.003	3	2
UCEC	INPP4B →	-0.273	-1.906	.017	.015	3	2
UCEC	Notch1 →	+0.132	+2.125	.008	.010	3	2
UCEC	Shc_pY317 →	-0.145	-2.000	.006	.003	3	2
UCEC	VHL →	-0.975	-2.087	<.001	.005	3	2
UCEC	Cyclin-B1 →	+0.462	+1.362	.019	.037	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

Gab2 by FUBP3 expression — UCEC

Explore this box plot interactively →