FUBP3

mutation — cross-omics
Cross-omicsMUTATION → DRUGCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FUBP3 mutation is significantly associated with the drug of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FUBP3-associated genes across cancer lineages are PRT062607, Y-39983, and AZD1208. Each is linked with FUBP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both FUBP3-to-partner and partner-to-FUBP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRT062607 grouped by FUBP3-low versus FUBP3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FUBP3→partner) and Y-score (partner→FUBP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEPRT062607 →+0.502+2.769.048.04021
LARGE_INTESTINEY-39983 →+0.446+2.652.040.04521
LARGE_INTESTINEAZD1208 →+0.393+2.649.022.04611
LARGE_INTESTINECP466722 →+0.409+2.652.039.04511
LARGE_INTESTINEUprosertib →+0.600+2.646.048.04711
LARGE_INTESTINEIRAK4_4710 →+0.427+2.649.018.04611
Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

PRT062607 by FUBP3 expression — LARGE_INTESTINE

Box plot of PRT062607 in FUBP3-low vs FUBP3-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration