FUBP1

Across TCGA patient cohorts, FUBP1 mutation is significantly associated with the RNA expression of many other genes, with 2,914 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FUBP1-associated genes across cancer lineages are RPL31P47, MRPS11, and DHFR. Each is linked with FUBP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both FUBP1-to-partner and partner-to-FUBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL31P47 grouped by FUBP1-low versus FUBP1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FUBP1→partner) and Y-score (partner→FUBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RPL31P47 →	+0.177	+4.631	<.001	.008	3	3
UCEC	MRPS11 →	+0.314	+1.822	.004	.004	3	3
UCEC	DHFR →	+0.642	+1.736	<.001	.007	3	3
UCEC	SLC25A11 →	+0.360	+3.186	.002	<.001	3	3
LGG	STARD4 →	+0.942	+3.700	<.001	.001	3	3
UCEC	UTP15 →	+0.405	+2.423	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,914 associations by consensus.

RPL31P47 by FUBP1 expression — LUAD

Explore this box plot interactively →