FUBP1

Across TCGA patient cohorts, FUBP1 mutation is significantly associated with the total protein of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FUBP1-associated genes across cancer lineages are FASN, EGFR_pY1068, and MEK1. Each is linked with FUBP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both FUBP1-to-partner and partner-to-FUBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FASN grouped by FUBP1-low versus FUBP1-high in LGG.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FUBP1→partner) and Y-score (partner→FUBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	FASN →	+0.254	+2.817	.014	.036	3	2
UCEC	EGFR_pY1068 →	-0.186	-1.700	.047	.042	3	2
UCEC	MEK1 →	+0.284	+1.765	.038	.014	3	2
UCEC	Rad50 →	-0.195	-1.415	.032	.046	3	2
UCEC	Annexin_VII →	-0.120	-2.169	.021	.003	3	2
UCEC	4E-BP1 →	+0.369	+2.169	<.001	.003	2	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

FASN by FUBP1 expression — LGG

Explore this box plot interactively →