FUBP1

Across TCGA cell cohorts, FUBP1 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FUBP1-associated genes across cancer lineages are LCE1C, SLC32A1, and TCF21. Each is linked with FUBP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FUBP1-to-partner and partner-to-FUBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LCE1C grouped by FUBP1-low versus FUBP1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FUBP1→partner) and Y-score (partner→FUBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	LCE1C →	+0.081	+4.684	<.001	.002	3	2
BLOOD_Leukemia	SLC32A1 →	+0.537	+3.901	.002	.006	3	1
BLOOD_Leukemia	TCF21 →	+0.015	+3.705	<.001	.007	3	1
BLOOD_Leukemia	CYP39A1 →	+0.261	+3.769	<.001	.008	3	1
BLOOD_Leukemia	LRIT1 →	+0.032	+4.269	<.001	.002	3	1
BLOOD_Leukemia	TACR3 →	+0.028	+4.060	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

LCE1C by FUBP1 expression — LARGE_INTESTINE

Explore this box plot interactively →