FTX

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FTX RNA expression is significantly associated with the protein abundance of many other proteins, with 17,101 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible FTX-associated proteins across cancer lineages are RPL26, FHL3, and RAB27A. Each is linked with FTX in more than 6 cancer types. Because this analysis shows association rather than direction, both FTX-to-partner and partner-to-FTX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FTX versus RPL26 in GBM, with a Pearson correlation of -0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FTX→partner) and Y-score (partner→FTX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMRPL26 →-0.760-0.682.004.00427
OVFHL3 →+0.717+0.626<.001.00736
GBMRAB27A →-0.635-0.556<.001<.00135
BRCAKANK2 →+0.563+0.736<.001<.00135
BRCARPL6 →-0.396-0.546<.001<.00135
GBMRPS6 →-0.356-0.388.005.00235
Each partner links to its Q-omics profile. Showing the 6 strongest of 17,101 associations by consensus.

FTX vs RPL26 — GBM

Per-sample scatter of FTX vs RPL26 in GBM (Pearson r = -0.47).

Explore this scatter interactively →

Exploration